A parabolic-elliptic-hyperbolic system of Keller-Segel type: numerical analysis and simulation (Preprint)

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Type: Preprint
National /International: International
Title: A parabolic-elliptic-hyperbolic system of Keller-Segel type: numerical analysis and simulation
Publication Date: 2026-01-21
Authors: - Augusto Manuel de Oliveira Fernandes
- José Augusto Ferreira
- Gonçalo Pena
Abstract:

This paper aims to study, from a numerical point of view, a system of partial differential equations defined by a parabolic, an elliptic and a hyperbolic equation that can be used to describe cell migration in elastic tissues that integrates chemotaxis, interstitial fluid pressure and tissue displacement. The system couples a Keller-Segel type system for cell density and chemical concentration with an elliptic equation for fluid pressure and a wave-type equation for displacement. We propose a semidiscrete nonuniform finite difference method to approximate the continuous system.
Furthermore, we derive second-order spatial error estimates for all system variables using a suitable discrete norm. Finally, numerical simulations validate the theoretical results and demonstrate the interplay between chemotaxis and tissue mechanics.

Institution: DMUC 26-03
Online version: http://www.mat.uc.pt...prints/eng_2026.html
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