Assuming that Aberrant Crypt Foci (ACF) in the colon are consequence of accumulation of abnormal cells we will characterize the dynamics of these cells, in order to describe the evolution of ACF. The colon  will be considered as a periodic spread  structure composed by a crypt and a intercryptal region. The evolution of such cells is described using a PDE Multiscale model.

(joint work with Isabel N. Figueiredo and Carlos Leal)